| 名稱 | RB1 p.E204Kfs*10 Reference Standard 標(biāo)準(zhǔn)品 |
| 型號 | CBP10451 |
| 報(bào)價(jià) |  |
| 特點(diǎn) | RB1 Reference Standard |
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基因檢測標(biāo)準(zhǔn)品 > Mutation > CBP10451RB1 p.E204Kfs*10 Reference Standard 標(biāo)準(zhǔn)品
- 詳細(xì)內(nèi)容
CBP10451 | |
| Gene | RB1 |
| Description | RB1, retinoblastoma-associated protein, is a key negative regulator of the G1 to S transition during cell division (PMID: 15084261) and also plays a role in cell differentiation, survival, senescence, epigenetic regulation, and genome stability (PMID: 21295686, PMID: 23359405, PMID: 22293180). Inactivation of Rb1 and loss of Rb1 tumor suppressor function has been identified in many early stage cancers (PMID: 26160835). |
| Technical Data | |
| DNA Change | c.610delG |
| AA Change | p.E204Kfs*10 |
| Mutation type | Splice_Site |
| Zygosity | Homozygous |
| Allelic Frequency | 100.00% |
| Transcript | ENST00000267163.4 |
| Cosmic ID | N/A |
| Chr position(GRCh37) | chr13:48934155 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |
|
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
