| 名稱 | PIK3CA p.Q546R Reference Standard 標(biāo)準(zhǔn)品 |
| 型號 | CBP10325 |
| 報(bào)價(jià) |  |
| 特點(diǎn) | PIK3CA p.Q546R Reference Standard |
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基因檢測標(biāo)準(zhǔn)品 > Mutation > CBP10325PIK3CA p.Q546R Reference Standard 標(biāo)準(zhǔn)品
- 詳細(xì)內(nèi)容
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CBP10325 | |
| Format | Genomic DNA |
| Description | PIK3CA Q546R lies within the helical domain of the Pik3ca protein (PMID: 24559118). Q546R has not been biochemically characterized, but is predicted to confer a gain of function to the Pik3ca protein as demonstrated by increased cell survival and transforming ability in cell culture (PMID: 26627007, PMID: 29533785). |
| Technical Data | |
| DNA Change | c.1637A>G |
| AA Change | p.Q546R |
| Mutation type | Substitution - Missense |
| Zygosity | Heterozygous |
| Allelic Frequency | 50.00% |
| Transcript | NM_006218.1 |
| Cosmic ID | COSM12459 |
| Chr position(GRCh37) | chr3:178936095 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |
|
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
